Hello Dear My Siblings, I 've been thinking about That difference for a few weeks ago, Sometimes it made Struggling to use,But after doing some researches I came to understand something like: We use "You and I"" in this case, S+V+V (Eg: you and I are friends(at the biginning ), so ""You and me" C +V+(by)+S , Eg:it was you and me(at the end).

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